Exploring Gene Therapy for OAB

See how we are demonstrating our commitment to patients with overactive bladder (OAB) with the investigation of a novel gene therapy (URO-902).

View URO-902 MOA

Discovering vibegron for OAB

Beta-3 adrenergic receptor agonists have been shown to be efficacious in the management of overactive bladder (OAB). Find out how our ongoing efforts to develop innovative therapies led to the discovery of vibegron.

View Vibegron MOA
View Vibegron MOA Thumbnail

Our Mission

At Urovant Sciences, we’ve made it our mission to keep patient health and well-being front and center. As part of this effort, our Medical Affairs team plays a vital role in providing the scientific support and resources needed to assist you where it matters most for patients.

Our Medical Science Liaisons (MSLs) are always available and would welcome the opportunity to meet with you. Just click below to schedule an appointment at your convenience.

Connect with an MSL

About OAB

Overactive bladder is a symptom complex that is generally not life-threatening yet compromising to everyday life.


Overactive bladder affects ≈35 million people in the US and significantly impairs activities of daily living.1,2


An internet-based survey study among 20,000 US adults ≥40 years found the overall prevalence of OAB to be 23%.1


The study found the overall prevalence of OAB in those affected at least “sometimes” to be 43.1% in women and 27.2% in men. The study found prevalence to increase with age to 49.4% among men ≥76 years of age and 51.2% among women ≥76 years of age.1

OAB Overview Monograph

Click below to find out more about the impact of OAB on quality of life, as well as the clinical and economic burden it has on those who live with this condition.

Read Monograph

Download PDF

Treatment Approaches in OAB

American Urological Association (AUA) treatment guidelines include many strategies to help control OAB. Patients and physicians have disease management options, from behavioral and lifestyle changes, pharmacologic management, and neurostimulation to surgery (in rare, refractory cases).

OAB Treatment Journey

OAB Treatment Monograph

Click below to dive deeper into the treatment journey for idiopathic OAB and to review the four different treatment lines and the pharmacologic options available.

Read Monograph

Download PDF

Discover Our Pipeline

Urovant Sciences is currently studying vibegron for an additional indication. Separately, the company initiated a Phase 2 study of a novel gene therapy.

Learn More

* Estimates are based on 23% prevalence rate from the EpiLUTS study and 2018 US Census Bureau population number projections for 2018.

1. Coyne KS, Sexton CC, Vats V, Thompson C, Kopp ZS, Milsom I. National community prevalence of overactive bladder in the United States stratified by sex and age. Urology. 2011;77(5):1081–1087.
2. US Census Bureau. Age and Sex Composition: 2018. Available at: https://data.census.gov/cedsci/table?q=people%20by%20age%20group&t=Age%20and%20 Sex&tid=ACSST1Y2018.S0101&hidePreview=false. Accessed November 4, 2020.

Tell us what interests you

How interested are you in learning more about the following topics?

The hypothetical role of targeted gene therapy in modulating BK channel expression
The role of beta-3 adrenergic receptor agonists in the treatment of patients with OAB
A comprehensive treatment overview for OAB
Treatment approaches in OAB
Recent publications on vibegron and OAB


We’ve received your completed survey. Thanks for participating.


Thank You.

We’ve received your inquiry. Thank you for contacting Urovant Sciences Medical Affairs. We will contact you shortly.


Take Survey

Welcome to
Urovant Sciences Medical Affairs

This site is intended as an educational resource for U.S. healthcare providers. The content may include information about products or potential uses that have not been approved by the U.S. Food and Drug Administration.

This information is not intended to be promotional or deliver medical advice.

Choose an option:

I’m a U.S. healthcare professional I’m a U.S. patient or caregiver